Promising Practices Promising PracticesPromising Practices
A forum for government's best ideas and most innovative leaders.

Photo: Why We're So Excited About Stem Cells

ARCHIVES
Courtesy of Dr. Ole Isacson, McLean Hospital and Harvard Medical School.

Certainly – as you can see here – stem cells are spectacularly beautiful. But they also hold spectacular promise for medicine.  That’s why I immediately expressed my enthusiasm for last week's Supreme Court ruling that effectively enables NIH to continue conducting and funding responsible, scientifically worthy stem cell research.

There are many kinds of stem cells. This is a picture of induced pluripotent stem cells – or,iPS cells. Investigators have recently begun using iPS cells to model several neurological diseases – including Parkinson’s. The cells here have been treated with growth factors that coax them into becoming the dopamine producing (dopaminergic) neurons lost in Parkinson’s. The colorized markers indicate the presence of three proteins found within dopaminergic neurons: (1) the enzyme needed to produce dopamine (tyrosine hydroxylase, inblue), (2) a structural protein specific to neurons (Type III beta-tubulin, in green), and (3) a gene regulatory protein needed in dopaminergic neurons (FOXA2, in red). The color-mixing in some cells indicates that all three proteins are present – confirming that these cells are on their way to becoming dopaminergic neurons.

Today’s image is more than just a pretty picture. It’s a window into the ways that disease affects the body – and possibly the ways we might counter those affects. The NIH/NINDS web site has more information about how iPS cells are being used to study Parkinson’s and other neurological disorders.

Francis S. Collins, M.D., Ph.D. is the Director of the National Institutes of Health (NIH). In that role he oversees the work of the largest supporter of biomedical research in the world, spanning the spectrum from basic to clinical research. Dr. Collins is a physician-geneticist noted for his landmark discoveries of disease genes and his leadership of the international Human Genome Project, which culminated in April 2003 with the completion of a finished sequence of the human DNA instruction book. He served as director of the National Human Genome Research Institute at the NIH from 1993-2008.

FROM OUR SPONSORS
JOIN THE DISCUSSION
Close [ x ] More from GovExec
 
 

Thank you for subscribing to newsletters from GovExec.com.
We think these reports might interest you:

  • Sponsored by G Suite

    Cross-Agency Teamwork, Anytime and Anywhere

    Dan McCrae, director of IT service delivery division, National Oceanic and Atmospheric Administration (NOAA)

    Download
  • Data-Centric Security vs. Database-Level Security

    Database-level encryption had its origins in the 1990s and early 2000s in response to very basic risks which largely revolved around the theft of servers, backup tapes and other physical-layer assets. As noted in Verizon’s 2014, Data Breach Investigations Report (DBIR)1, threats today are far more advanced and dangerous.

    Download
  • Sponsored by One Identity

    One Nation Under Guard: Securing User Identities Across State and Local Government

    In 2016, the government can expect even more sophisticated threats on the horizon, making it all the more imperative that agencies enforce proper identity and access management (IAM) practices. In order to better measure the current state of IAM at the state and local level, Government Business Council (GBC) conducted an in-depth research study of state and local employees.

    Download
  • Sponsored by Aquilent

    The Next Federal Evolution of Cloud

    This GBC report explains the evolution of cloud computing in federal government, and provides an outlook for the future of the cloud in government IT.

    Download
  • Sponsored by LTC Partners, administrators of the Federal Long Term Care Insurance Program

    Approaching the Brink of Federal Retirement

    Approximately 10,000 baby boomers are reaching retirement age per day, and a growing number of federal employees are preparing themselves for the next chapter of their lives. Learn how to tackle the challenges that today's workforce faces in laying the groundwork for a smooth and secure retirement.

    Download
  • Sponsored by Hewlett Packard Enterprise

    Cyber Defense 101: Arming the Next Generation of Government Employees

    Read this issue brief to learn about the sector's most potent challenges in the new cyber landscape and how government organizations are building a robust, threat-aware infrastructure

    Download
  • Sponsored by Aquilent

    GBC Issue Brief: Cultivating Digital Services in the Federal Landscape

    Read this GBC issue brief to learn more about the current state of digital services in the government, and how key players are pushing enhancements towards a user-centric approach.

    Download

When you download a report, your information may be shared with the underwriters of that document.